Empirical Research on the Relationship between Foreign Trade Growth and Cross-Border Electronic Commerce in Fujian Province

Based on the of domestic and foreign scholars\u27 researches, foreign trade growth has a booming effect on economic development, otherwise, the role of cross-border electronic commerce developing in international trade business and economic still has not been proved by the actual data available. This essay selects quarterly data of foreign trade and cross-border electronic commerce in Fujian Province who has the advantages of foreign trade, to makeup the VEC model and research the relationship between the growth of foreign trade and cross-border e-commerce, the results show that: there is the long-term interactive relationship between foreign trade growth and cross-border electronic commerce. Cross-border electronic commerce in Fujian province is only starting, needing more positive and long-term policies to promote

Exemplar-based Linear Discriminant Analysis for Robust Object Tracking

Tracking-by-detection has become an attractive tracking technique, which treats tracking as a category detection problem. However, the task in tracking is to search for a specific object, rather than an object category as in detection. In this paper, we propose a novel tracking framework based on exemplar detector rather than category detector. The proposed tracker is an ensemble of exemplar-based linear discriminant analysis (ELDA) detectors. Each detector is quite specific and discriminative, because it is trained by a single object instance and massive negatives. To improve its adaptivity, we update both object and background models. Experimental results on several challenging video sequences demonstrate the effectiveness and robustness of our tracking algorithm.Comment: ICIP201

Improving the resilience of post-disaster water distribution systems using a dynamic optimization framework

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Improving the resilience of water distribution systems (WDSs) to handle natural disasters (e.g., earthquakes) is a critical step towards sustainable urban water management. This requires the water utility to be able to respond quickly to such disaster events and in an organized manner, to prioritize the use of available resources to restore service rapidly whilst minimizing the negative impacts. Many methods have been developed to evaluate the WDS resilience, but few efforts are made so far to improve resilience of a post-disaster WDS through identifying optimal sequencing of recovery actions. To address this gap, a new dynamic optimization framework is proposed here where the resilience of a post-disaster WDS is evaluated using six different metrics. A tailored Genetic Algorithm is developed to solve the complex optimization problem driven by these metrics. The proposed framework is demonstrated using a real-world WDS with 6,064 pipes. Results obtained show that the proposed framework successfully identifies near-optimal sequencing of recovery actions for this complex WDS. The gained insights, conditional on the specific attributes of the case study, include: (i) the near-optimal sequencing of recovery strategy heavily depends on the damage properties of the WDS, (ii) replacements of damaged elements tend to be scheduled at the intermediate-late stages of the recovery process due to their long operation time, and (iii) interventions to damaged pipe elements near critical facilities (e.g., hospitals) should not be necessarily the first priority to recover due to complex hydraulic interactions within the WDS

Etiologic analysis of Chinese patients with agranulocytosis and hematopathies infected with resistant bacteria: Antibacterial effect of tigecycline

Purpose: To assess the etiologic characteristics of resistant bacterial infections occurring in agranulocytosis patients with hematopathies, and to determine the effect of tigecycline (TGC).Methods: After ineffective treatment with carbapenem, all of the patients were divided into the following three groups: TGC alone (15 cases); TGC as initial treatment, followed by a combination with other antibiotics (40 cases); and TGC in combination with other antibiotics from the start of treatment (71 cases).Results: Among the 126 patients, 108 had fevers (85.71 %). The most common infection site was lung, accounting for 71.43 % of all infections. A total of 52 pathogens were isolated from 126 hospitalized patients, including 38 Gram-negative bacteria (70.37 %), 14 Gram-positive bacteria (25.93 %), and 2 fungi (3.70 %). TGC treatment efficacy was 50.79 %. There were no statistically significant differences between the three treatment groups (p = 0.473). Adverse drug reaction was nausea and vomiting (14.29 %), nausea without vomiting (11.90 %), diarrhea (6.35 %), and generalized skin rash with itching (3.17 %).Conclusion: TGC is effective in treating neutropenic patients with hematopathies who are infected with resistant bacteria. The side effects of TGC are few; thus, TGC is safe and generally well-tolerated.Keywords: Tigecycline, Agranulocytosis, Resistant bacteria, Hematopathy, Neutropenic patient

Comparison of bypass surgery and drug-eluting stenting in diabetic patients with left main and/or multivessel disease: A systematic review and meta-analysis of randomized and nonrandomized studies

Background: With advances in theinterventional field, the choice between coronary artery bypass grafting (CABG) and percutaneous coronary intervention with drug-eluting stents (PCI-DES) for the diabetic subset with left main (LM) and/or multivessel disease (MVD) remains consistently controversial. Methods and results: We conducted a systematic review of randomized controlled trials (RCTs) and observational controlled trials (OCTs) comparing the two strategies for the diabetic subset with LM and/or MVD. PubMed, EMBASE, CENTRAL databases, Google Scholar and SinoMed were systematically searched for eligible studies without language and publica­tion restrictions. We identified 19 trials (4 randomized and 15 nonrandomized), enrolling 5,805 patients in OCTs and 3,060 patients in RCTs, respectively. PCI-DES was associated with higher mortality compared with CABG (11.7% DES vs. 9.1% CABG, RR 1.23, 95% CI 1.00–1.53, p = 0.06). Patients after PCI-DES had higher prevalence of myocardial infarction (MI) when compared with CABG (8.5% DES vs. 4.6% CABG, RR 1.68, 95% CI 1.20–2.37, p = 0.003). PCI-DES patients were at substantially lower risk of stroke (2.0% DES vs. 3.9% CABG, RR 0.51, 95% CI 0.39–0.67, p < 0.00001), but at several-fold higher risk of repeat revascularization (19.0% DES vs. 6.3% CABG, RR 2.95, 95% CI 2.46–3.55, p < 0.00001). The OCT patients risked a lower mortality as compared to the RCT patients (9.6% OCTs vs. 11.9% RCTs, RR 0.81, 95% CI 0.71–0.92, p = 0.001). Conclusions: CABG for patients with diabetes mellitus and LM and/or MVD had advan­tages over PCI-DES in all-cause death, nonfatal MI, and repeat revascularization, but the substantial disadvantage in nonfatal stroke. The high-selected patients (RCTs) risked a higher mortality than the real-world patients (OCTs)

Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure.

To maintain healthy mitochondrial enzyme content and function, mitochondria possess a complex protein quality control system, which is composed of different endogenous sets of chaperones and proteases. Heat shock protein 60 (HSP60) is one of these mitochondrial molecular chaperones and has been proposed to play a pivotal role in the regulation of protein folding and the prevention of protein aggregation. However, the physiological function of HSP60 in mammalian tissues is not fully understood. Here we generated an inducible cardiac-specific HSP60 knockout mouse model, and demonstrated that HSP60 deletion in adult mouse hearts altered mitochondrial complex activity, mitochondrial membrane potential, and ROS production, and eventually led to dilated cardiomyopathy, heart failure, and lethality. Proteomic analysis was performed in purified control and mutant mitochondria before mutant hearts developed obvious cardiac abnormalities, and revealed a list of mitochondrial-localized proteins that rely on HSP60 (HSP60-dependent) for correctly folding in mitochondria. We also utilized an in vitro system to assess the effects of HSP60 deletion on mitochondrial protein import and protein stability after import, and found that both HSP60-dependent and HSP60-independent mitochondrial proteins could be normally imported in mutant mitochondria. However, the former underwent degradation in mutant mitochondria after import, suggesting that the protein exhibited low stability in mutant mitochondria. Interestingly, the degradation could be almost fully rescued by a non-specific LONP1 and proteasome inhibitor, MG132, in mutant mitochondria. Therefore, our results demonstrated that HSP60 plays an essential role in maintaining normal cardiac morphology and function by regulating mitochondrial protein homeostasis and mitochondrial function